Forthcoming in Vaccine. Abstract only; full text available to subscribers.
Projected health benefits and costs of pneumococcal and rotavirus vaccination in Uganda
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Jacqueline E. Tatea, , , Annet Kisakyeb, Prosper Mugyenyic, Diana Kizzad, Amos Odiite and Fiona Brakaf
a Centers for Disease Control and Prevention, 1600 Clifton Rd. NE, MS-A47, Atlanta, GA 30333, USA
b World Health Organization Country Office Uganda, Uganda
c Ministry of Health/Uganda National Expanded Programme on Immunization, Kampala, Uganda
d Sabin Vaccine Institute, Kampala, Uganda
e Mulago National Referral Hospital, Kampala, Uganda
f World Health Organization Country Office Ethiopia, Ethiopia
We determined impact and cost-effectiveness of pneumococcal and rotavirus vaccination programs among children < 5 years of age in Uganda from the public health system perspective. Disease-specific models compared the disease burden and cost with and without a vaccination program. If introduced, pneumococcal and rotavirus vaccine programs will save 10,796 and 5265 lives, respectively, prevent 94,071 Streptococcus pneumoniae and 94,729 rotavirus cases in children < 5 years, and save 3886 and 996 million Ugandan shillings ($2.3 and $0.6 million US dollars), respectively, in direct medical costs annually. At the GAVI price ($0.15/dose), pneumococcal vaccine will be cost-saving and rotavirus vaccine highly cost-effective.