<< Back To Home


Thursday, 20th of June 2013 Print

 Abstract below; full text is at  http://www.ijmr.org.in/text.asp?2013/137/1/15/108268




Dogra S, Narang T, Kumar B. Leprosy - evolution of the path to eradication. Indian J Med Res [serial online] 2013 [cited 2013 Jun 19];137:15-35. Available from: http://www.ijmr.org.in/text.asp?2013/137/1/15/108268

Leprosy is among the worlds oldest and most dreaded diseases and it has been synonymous with stigma and discrimination due to the hideous deformities it produced, mystery around its aetiology and transmission and lack of any effective remedy till recently. Leprosy control started with the use of chaulmoogra oil and for the last three decades, multi drug therapy (MDT) has been our main tool against leprosy. In the last two decades, the reported global prevalence of active leprosy infection has dropped by almost 90 per cent by the combined efforts of the World Health Organization (WHO), local governments, health professionals, and non-governmental organizations (NGOs), however, a parallel drop in the incidence or new case detection rate (NCDR) has not occurred. From 1994 through 2011, more than 100,000 new cases are being detected annually, of whom maximum case load is from India. There is need for research on tools for early diagnosis, short and effective treatment, and prevention of deformities and disabilities. Evaluating the role of immunotherapy and immunoprophylaxis will also lead us to better understanding of their mode of action. Further molecular analysis of Mycobacterium leprae genome may provide the requisite basis for all this. The current reality is that there is a need to sustain and provide quality leprosy services to all persons through general health services, including good referral system. All these provisions in the integrated health care approach will go a long way in further reducing the stigma. Efforts need to be made to reduce deformity through early detection, self care, physiotherapy and reconstructive surgery and developing sound surveillance systems. With all the remarkable achievements in the fight against leprosy, the stage is now set for the final assault. It is hoped that with the efforts of all the stake holders and strong political will, the disease will be eradicated in the near future.

Keywords: Deformity - Hansen′s disease - leprosy - MDT - multibacillary - Mycobacterium leprae - paucibacillary - reconstructive surgery 



To subscribe or unsubscribe from these Child Survival Updates, pls contact kidsurvival@gmail.com. If you unsubscribe, indicate from which E mail address you are receving these updates.


When subscribing, write from your most permanent E-mail address, not always that of your current employer.

Do not subscribe on behalf of friends or colleagues; forward updates to them for their decision.

Those wishing to read only malaria updates should subscribe at


Those wishing to read only vaccination updates should subscribe at kidsurvivalvaccination@gmail.com




If you have a comment you want posted, send to rdavis@africamail.com